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FGFR2, also named CD332, is a transmembrane protein and belongs to the fibroblast growth factor receptors family (FGFR family), which are mitogenic signaling molecules that have roles in important processes such as cell division, regulation of cell growth and mutation, the formation of blood vessels, wound healing, and embryonic development. FGFR2 is a transmembrane catalytic receptor with intracellular tyrosine kinase activity, similar to FGFRs. The FGFR2 gene is located on human chromosome 10 and expresses two slightly different subtypes: FGFR2IIIb, which is mainly expressed in epithelial cells, and FGFR2IIIc, which is mainly expressed in mesenchymal cells. |
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